On this page you will find all our current recommendations, initially sorted by published date. The table headings are active links that will sort the information in ascending or descending order. Please note that all our recommendations are valid unless they are superseded by NICE or national guidance.

If you are a healthcare professional working with the GM region and would like to submit information for a recommendation to be reviewed then please contact the professional secretary to the group.

Please note that the new drug recommendations no longer contain a review date as they will be reviewed as and when substantial new evidence that may change the original recommendation becomes available. This will be highlighted through regular horizon scanning activities. All previous review dates on old recommendations are invalid as they will also be reviewed as outlined. In addition if a NICE TA is published then the new drug recommendation will be superseded by the NICE TA – these recommendations will be moved to the archive recommendation section of the website within 90 days of the NICE TA being issued.

Document Title Issue Date Review Date Status

Mental health

Promazine position statement 20251211 Dec 2025
Promazine patient information leaflet 20251211 Dec 2025

Cardiovascular

Comparison of DOACs for atrial fibrillation 20230611 Jun 2023 External link, login required
Statins for the prevention of cardiovascular disease in people living with HIV 20240811 Aug 2024 20270511 May 2027

Gastroenterology

Fidaxomicin (Dificlir®) for the treatment of Clostridium difficile infection 20191011 Oct 2019 Final
Octreotide for treatment of certain gastrointestinal indications 20180511 May 2018
Ustekinumab dose escalation for Crohn's disease and ulcerative colitis 20230911 Sep 2023 v3.1

Diabetes & Endocrinology

NHS GM Continuous glucose monitoring (CGM) prescribing guidance 20251011 Oct 2025 See the Clinical Guidance and Pathways page for more resources relating to diabetes.
Xultophy® (Liraglutide +Insulin Degludec) for the treatment of adults with T2DM 20150511 May 2015 Under review
Liothyronine injection commissioning statement 20200711 Jul 2020 20230711 Jul 2023 Final
Vitamin D statement 20160911 Sep 2016 Under review
Vitamin D for Insufficiency & Deficiency (adults) Under review
Vitamin D for Insufficiency & Deficiency (paediatrics) Under review

Obstetrics, gynaecology, and urinary-tract disorders

Levonorgestrel-containing intrauterine systems 20240511 May 2024 20270511 May 2027 Update in progress

Neurology

Levetiracetam position statement on generic prescribing 20251211 Dec 2025 20281211 Dec 2028
Melatonin for primary insomnia (adults) 20080911 Sep 2008 Final

Musculoskeletal

Denosumab 60mg biosimilars - Interim Position Statement 20260311 Mar 2026 20290111 Jan 2029
Dibotermin alfa (InductOs®) for the treatment of non-union fracture 20190911 Sep 2019 Final

Haematology

Rituximab for Treatment of Refractory Primary Idiopathic Immune Cytopenias 20180511 May 2018

Wound management

PICO® dressings for difficult to manage wounds 20150511 May 2015 Final

Immunology

Omalizumab for chronic inducible urticarias 20231111 Nov 2023 20261111 Nov 2026