On this page you will find all our current recommendations, initially sorted by published date. The table headings are active links that will sort the information in ascending or descending order. Please note that all our recommendations are valid unless they are superseded by NICE or national guidance.

If you are a healthcare professional working with the GM region and would like to submit information for a recommendation to be reviewed then please contact the professional secretary to the group.

Please note that the new drug recommendations no longer contain a review date as they will be reviewed as and when substantial new evidence that may change the original recommendation becomes available. This will be highlighted through regular horizon scanning activities. All previous review dates on old recommendations are invalid as they will also be reviewed as outlined. In addition if a NICE TA is published then the new drug recommendation will be superseded by the NICE TA – these recommendations will be moved to the archive recommendation section of the website within 90 days of the NICE TA being issued.

Document Title Issue Date Review Date Status

Cardiovascular

Edoxaban for the Treatment of Non Valvular Atrial Fibrillation 20221109 Nov 2022 20250409 Apr 2025

Ophthalmology

Bevacizumab in AMD updated 20151109 Nov 2015 Ophthalmology pathway under review

Gastroenterology

Fidaxomicin (Dificlir®) for the treatment of Clostridium difficile infection 20191009 Oct 2019 Final
Octreotide for treatment of certain gastrointestinal indications 20180509 May 2018
Ustekinumab dose escalation for Crohn's disease and ulcerative colitis 20211109 Nov 2021 v3.0

Diabetes

Blood Glucose Testing Strips Evaluation 20171209 Dec 2017 Under review
FreeStyle Libre® Flash Glucose Monitoring System. 20210209 Feb 2021 Under review
Xultophy® (Liraglutide +Insulin Degludec) for the treatment of adults with T2DM 20150509 May 2015 Under review

Obstetrics, gynaecology, and urinary-tract disorders

Levonorgestrel-containing intrauterine systems 20220909 Sep 2022 20250909 Sep 2025 Final

Neurology

Melatonin for primary insomnia (adults) 20080909 Sep 2008 Final

Musculoskeletal

Dibotermin alfa (InductOs®) for the treatment of non-union fracture 20190909 Sep 2019 Final
Metoject (methotrexate) Injection for RA 20081009 Oct 2008 Final

Haematology

Rituximab for Treatment of Refractory Primary Idiopathic Immune Cytopenias 20180509 May 2018

Wound management

PICO® dressings for difficult to manage wounds 20150509 May 2015 Final

Endocrine

Liothyronine injection commissioning statement 20200709 Jul 2020 20230709 Jul 2023 Final
Vitamin D statement 20160909 Sep 2016 Under review
Vitamin D for Insufficiency & Deficiency (adults) 20160309 Mar 2016 Under review
Vitamin D for Insufficiency & Deficiency (paediatrics) 20160409 Apr 2016 Under review