On this page you will find all our current recommendations, initially sorted by published date. The table headings are active links that will sort the information in ascending or descending order. Please note that all our recommendations are valid unless they are superseded by NICE or national guidance.

If you are a healthcare professional working with the GM region and would like to submit information for a recommendation to be reviewed then please contact the professional secretary to the group.

Please note that the new drug recommendations no longer contain a review date as they will be reviewed as and when substantial new evidence that may change the original recommendation becomes available. This will be highlighted through regular horizon scanning activities. All previous review dates on old recommendations are invalid as they will also be reviewed as outlined. In addition if a NICE TA is published then the new drug recommendation will be superseded by the NICE TA – these recommendations will be moved to the archive recommendation section of the website within 90 days of the NICE TA being issued.

Document Title Issue Date Review Date Status


Edoxaban for the Treatment of Non Valvular Atrial Fibrillation 20221103 Nov 2022 20250403 Apr 2025


Bevacizumab in AMD updated 20151103 Nov 2015


Bezlotoxumab▼ for the prevention of recurrence of Clostridium difficile infection in adults at high risk of recurrence. 20191003 Oct 2019 Final
Fidaxomicin (Dificlir®) for the treatment of Clostridium difficile infection 20191003 Oct 2019 Final
Octreotide for treatment of certain gastrointestinal indications 20180503 May 2018
Ustekinumab dose escalation for Crohn's disease and ulcerative colitis 20211103 Nov 2021 v3.0


Blood Glucose Testing Strips Evaluation 20171203 Dec 2017 Review postponed indefinitely
FreeStyle Libre® Flash Glucose Monitoring System. 20210203 Feb 2021 Under review
Insulin Degludec for Type 1 and 2 DM (updated) 20140503 May 2014 Final
Toujeo® Insulin Glargine 20190503 May 2019 Final
Xultophy® (Liraglutide +Insulin Degludec) for the treatment of adults with T2DM 20150503 May 2015 Final

Obstetrics, gynaecology, and urinary-tract disorders

Levonorgestrel-containing intrauterine systems 20220903 Sep 2022 Final


Melatonin for primary insomnia (adults) 20080903 Sep 2008 Final


Dibotermin alfa (InductOs®) for the treatment of non-union fracture 20190903 Sep 2019 Final
Metoject (methotrexate) Injection for RA 20081003 Oct 2008 Final


Rituximab for Treatment of Refractory Primary Idiopathic Immune Cytopenias 20180503 May 2018

Wound management

PICO® dressings for difficult to manage wounds 20150503 May 2015 Final


Liothyronine injection commissioning statement 20200703 Jul 2020 Final
Vitamin D statement 20160903 Sep 2016
Vitamin D for Insufficiency & Deficiency (adults) 20160303 Mar 2016 Final
Vitamin D for Insufficiency & Deficiency (paediatrics) 20160403 Apr 2016 Final